The Impact of Echocardiographic Screening for Rheumatic Heart Disease on Patient Quality of Life - 26/07/16
, Andrea Dantin, BS 2, Michelle Ploutz, MD 3, Twalib Aliku, MD 4, Peter Lwabi, MD 5, Craig Sable, MD 3, Andrea Beaton, MD 3Abstract |
Objective |
To assess the impact of rheumatic heart disease (RHD) on child-reported health-related quality of life (HRQOL) in the context of a Ugandan school-based echocardiographic screening program. Echocardiography-based screening has emerged as a tool for the early detection of RHD, but little is known about its impact on those screened.
Study design |
Participants included 358 children from Gulu and 28 children from Kampala Uganda. The Pediatric Quality of Life Inventory Version 4.0 was used to assess HRQOL in 4 groups of children: Gulu prescreen, Gulu postscreen, Gulu previously linked to care, and Kampala previously linked to care. Children in the pre- and postscreen groups were selected from a single school before and after screening occurred and matched by age and sex. Children previously linked to care were recruited from previous screening studies.
Results |
When the echocardiogram was normal, there was no difference in HRQOL in the prescreen and postscreen groups. In the postscreen group, identification of latent RHD resulted in lower physical (75.3 vs 68.3, P = .03) and emotional (71.7 vs 63.4, P < .01) HRQOL, despite a lack of symptoms. The Kampala group had longer linkage to care (42 months vs 6 months, P < .01) and demonstrated greater HRQOL scores compared with the Gulu-linked group (70.7 vs 77.8, P < .01) and the combined Gulu cohort (77.8 vs 69.4, P = .02).
Conclusions |
Echocardiography-based screening for RHD does not diminish HRQOL in Ugandan children; rather, a diminished HRQOL score may be associated with being identified as RHD positive. Further investigation is needed to understand if longer linkage to care may ultimately normalize or improve HRQOL.
Le texte complet de cet article est disponible en PDF.Keywords : health-related quality of life, quality of life, rheumatic heart disease
Abbreviations : HRQOL, PedsQL, PedsQLTM4.0, QOL, RHD
Plan
| Supported by the National Institutes of Health National Center for Advancing Translational Sciences (UL1TR000075 and KL2TR000076). Additional support provided by Gift of Life International/Rotary International. The contents of this article are the responsibility of the authors and do not necessarily represent the views of the National Center for Advancing Translational Sciences or the National Institutes of Health. |
Vol 175
P. 123-129 - août 2016 Retour au numéro
Article précédent
- Congenital Heart Defects and Measures of Fetal Growth in Newborns with Down Syndrome or 22q11.2 Deletion Syndrome
- Niels B. Matthiesen, Peter Agergaard, Tine B. Henriksen, Cathrine C. Bach, J. William Gaynor, Vibeke Hjortdal, John R. Østergaard
- Defining the Phenotype and Assessing Severity in Phosphoglucomutase-1 Deficiency
- Sunnie Yan-Wai Wong, Lesa J. Beamer, Therese Gadomski, Tomas Honzik, Miski Mohamed, Saskia B. Wortmann, Katja S. Brocke Holmefjord, Marit Mork, Francis Bowling, Jolanta Sykut-Cegielska, Dieter Koch, Amanda Ackermann, Charles A. Stanley, Daisy Rymen, Avraham Zeharia, Moeen Al-Sayed, Thomas Marquardt, Jaak Jaeken, Dirk Lefeber, Donald F. Conrad, Tamas Kozicz, Eva Morava
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?