Findrisk score has been validated for prediction of diabetes risk in many populations. The aim of this study was to examine the value of this score for the detection of dysglycemia (impaired fasting glucose and/or glucose intolerance or diabetes) in a high-risk population in Constantine (Algeria).

We had recruited 397 patients (281 women) with risk factors of diabetes, mean age 50.2±11.7 years. All had fasting glycemia (FG) and oral post charge glycemia (PCG). Findrisk score was calculated. Carotid femoral pulse wave velocity (PWV) was measured by Complior^® device.

FG and PCG were abnormal in 159 and 157 patients, respectively. Dysglycemia was found in 204 patients (51.4%), with diabetes in 17.6% and prediabetes in 33.8% of them. Findrisk score strongly correlated to FG (r=0.129, P=0.01) and PCG (r=0.193, P=10⁻⁵) but also to systolic (r=0.33) and diastolic blood pressure (r=0.20), and to PWV (r=0.29). Discriminating threshold of this score for predicting dysglycemia was 13. It was significantly associated with prediabetes (P=0.001) and dysglycemia (P=10⁻⁵), this association was found in women but not in men. Sensibility and specificity of this score for detecting dysglycemia were 76% and 37%, respectively. Their positive and negative predictive values were 54.7% and 60.7%, respectively.

FG and PCG detected dysglycemia in similar proportions. Identification of dysglycemia through Findrisk score was validated only in women. The correlation between Findrisk score and PWV suggests that a high score testified also of a high cardiovascular risk in these patients without glycemic abnormality or known cardiovascular history.