Paraneoplastic fibrillary glomerulonephritis associated with intrahepatic cholangiocarcinoma: When diagnosis of a rare kidney disease leads to successful hepatic cancer treatment - 08/02/17
, Anne Jolivot a, Maud Rabeyrin b, Valérie Hervieu b, Pierre-Jean Valette c, Jean-Yves Scoazec d, Jean-Michel Gougon e, Laurent Juillard a, Jérôme Dumortier fSummary |
A 50-year-old man presented with nephrotic syndrome. Electron microscopy analysis of a kidney biopsy specimen showed fibrillary glomerulonephritis, a rare glomerular disease, while histological analysis of a liver tumor biopsy confirmed an intrahepatic cholangiocarcinoma. The paraneoplastic nature of fibrillary glomerulonephritis is debated but after curative treatment of the hepatic nodule, remission of nephrotic syndrome was confirmed at 6-, 12- and 24-months follow-up. To our knowledge, this is the first description of a paraneoplastic fibrillary glomerulonephritis associated with a cholangiocarcinoma, supported by complete remission achieved following cancer treatment.
Le texte complet de cet article est disponible en PDF.Abbreviations : ALT, ANCA, Anti PLA2R antibodies, AST, CCa, CRP, eGFR, ESRD, FGN, RAS
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Vol 41 - N° 1
P. e8-e11 - février 2017 Retour au numéro
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