Non-culture based assays for the detection of fungal pathogens - 13/06/18
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Abstract |
Traditional, culture based methods for the diagnosis of fungal infections are still considered as gold standard, but they are time consuming and low sensitive. Therefore, in order to overcome the limitations, many researchers have focused on the development of new immunological and molecular based rapid assays that could enable early diagnosis of infection and accurate identification of fungal pathogens causing superficial and invasive infection. In this brief review, we highlighted the advantages and disadvantages of conventional diagnostic methods and possibility of non-culture based assays in diagnosis of superficial fungal infections and presented the overview on currently available immunochromatographic assays as well as availability of biomarkers detection by immunodiagnostic procedures in prompt and accurate diagnosis of invasive fungal infections. In addition, we presented diagnostic efficiency of currently available molecular panels and researches in this area.
Le texte complet de cet article est disponible en PDF.Keywords : Fungal infection, Rapid detection, Conventional assays, Immunoassays, Molecular assays
Plan
Vol 28 - N° 2
P. 236-248 - juin 2018 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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