Effect of intra-articular Botulinum toxin injections on temporo-mandibular joint pain - 17/09/18
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Abstract |
Temporo-mandibular joint dysfunction can be painful and disabling. In some cases, it is refractory to classical treatment. Intra-articular Botulinum toxin injections have been shown to have an anti-inflammatory and analgesic effect. The aim of this study was to evaluate the effectiveness of such injections on severe, refractory temporo-mandibular joint pain. This was a retrospective study. Patients were included if they still had joint pain≥5 on a Visual Analogue Scale following completion of all other treatments. A complete treatment protocol (including physiotherapy, tongue splints, intra muscular injections of Botulinum toxin and injections of hyaluronic acid, excluding surgery) having being done before the injection of 30 Botox* units (Botulinum toxin A), the treatment being considered clinically successful if the Visual Analogue Scale decreases by at least 2 points. Seventy-seven patients were included. Sixty-six percent of patients have a significant reduction in pain at 1 month which lasted at least until 3 months. Mouth opening and quality of life also improved. Moreover, no complications were reported. Further randomized, controlled studies are needed to confirm the results, however this study suggests intra-articular injection of Botulinum toxin is a safe and effective treatment for severe, refractory temporo-mandibular joint pain, avoiding surgery.
Le texte complet de cet article est disponible en PDF.Keywords : Botulinum toxin, Pain, Temporo-Mandibular joint, Intra-articular injections, Analgesic effect
Plan
☆ | This work has already been presented in congress: Batifol D, El Najjar F, Harding-Kaba B, Goudot P, Yachouh J (2010). Injection de toxine botulique intra-articulaire: action antalgique. Paper presented at the 46th Congress of the “Société française de stomatologie et chirurgie maxillo-faciale”, 30 Sept–2 Oct 2010, Paris (France). Batifol D (2014). Intra-articular injection of botulinum toxin analgesic effect. Paper presented at the 3rd International Conference and exhibition on Orthopedics and Rheumatology, July 28–30, 2014, San Francisco (USA). |
Vol 119 - N° 4
P. 319-324 - septembre 2018 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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