What is pharmacoepidemiology? Definition, methods, interest and clinical applications - 01/11/18
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Summary |
Clinical evaluation of drugs before approval is based on the experimental design of clinical trial with randomization of drug exposure. Unfortunately, conclusions of clinical trials are necessarily limited to patients included into the trials. It is thus necessary to compare these experimental data coming from clinical trials with the real use of drugs in clinical practice. Pharmacoepidemiology is the study of interactions between drugs and human populations, investigating, in real conditions of life, benefits, risks and use of drugs. Pharmacoepidemiology applies to drugs the methods and/or reasoning of both pharmacology and epidemiology. The development of pharmacoepidemiology should improve the “rational drug use”.
Le texte complet de cet article est disponible en PDF.Keywords : Drugs, Pharmacoepidemiology, Efficacy, Effectiveness, Drug risk, Clinical evaluation, Adverse drug reactions
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