The present research is undertaken with the purpose of studying interrelation of frustration of a sexual desire and a mental pathology with definition of their clinical features at patients of both floors and an establishment of the factors promoting occurrence and development of infringements libido, development of complex therapeutic actions.

The basic methods of research clinical-psychopathological and clinical-sexological. Also in research have been used statistical methods.

At complex studying at 32 patients (21 man and 11 women), addressed in branch of sexual pathology of the Moscow scientific research institute of psychiatry, in the age of from 22 till 55 years as a result of clinical inspection, agree ICD-10, have been revealed sexual infringements F52.0 “Absence or loss of a sexual inclination” (37,5%), F52.10 “Sexual disgust” (21,9%), F52.11 “Absence of sexual satisfaction”, including sexual angedonia (28,1%), F52.7 “Increased sexual inclination” (12,5%) in frameworks F21 “Shizotypical frustration” (46,9%), F60 “Specific frustration of the person) (22,8%), F4 “Neurotic, connected with stress and? ?? ?? ?? ?? ?? ?? frustration”(16,7%), F0“Organic, including symptomatic, mental frustration” (15,6%).

As frustration of a sexual inclination at researched patients has been caused by mental infringements, as conducting (leading) methods in medical - rehabilitation actions has been elected psychopharmaco-and psychotherapy.