Work impairment in bipolar disorder patients – results from a two-year observational study (EMBLEM)
C. Reed a 
, I. Goetz a, E. Vieta b, M. Bassi c, J.M. Haro d
the EMBLEM Advisory Board
Voir les affiliationsBienvenue sur EM-consulte, la référence des professionnels de santé.
L'accès au texte intégral de ce chapitre nécessite l'achat du livre ou l'achat du chapitre.
| pages | 7 |
| Iconographies | 1 |
| Vidéos | 0 |
| Autres | 0 |
Abstract
Objectives
To explore factors associated with work impairment at 2 years following an acute episode.
Methods
European Mania in Bipolar disorder Longitudinal Evaluation of Medication (EMBLEM) is a prospective, observational study on the outcomes of patients with a manic/mixed episode. Work impairment was measured using a Longitudinal Interval Follow-up Evaluation (slice of LIFE) item and patients were categorised with either low or high work impairment at each observation. Baseline factors associated with work impairment at 2 years were assessed using multivariate modelling.
Results
At baseline (n=2289), 69% of patients had high work impairment. At 2 years (n=1393), high impairment reduced to 41%. Modelling identified rapid cycling as the strongest disease-related factor associated with high work impairment at 2 years, although high work impairment at baseline had the strongest association overall. Lower levels of education, recent admissions, CGI-BP overall severity in the 12 months prior to baseline and CGI-BP mania at baseline all predicted higher work impairment. Living together in a relationship and independent housing were both significantly associated with having low work impairment at 2 years.
Conclusions
Work impairment in bipolar disorder is maintained over long periods, and is strongly associated with relationship status, living conditions and various disease-related factors.
Keywords : Bipolar disorder, Longitudinal study, Mania, Work impairment, Functional outcomes
Plan
Vol 25 - N° 6
P. 338-344 - octobre 2010 Retour au numéro
Article précédent
- Mindfulness-based cognitive therapy for bipolar disorder: A feasibility trial
- B. Weber, F. Jermann, M. Gex-Fabry, A. Nallet, G. Bondolfi, J.-M. Aubry
- Brain imaging findings in children and adolescents with mental disorders: A cross-sectional review
- S. Mana, M.-L. Paillère Martinot, J.-L. Martinot
Bienvenue sur EM-consulte,
la référence des professionnels de santé.
Plus de 500 000 articles médicaux,
paramédicaux et scientifiques vous attendent.
L'accès au texte intégral de cet article nécessite un abonnement ou un achat à l'unité.
Déjà abonné à cette revue ?