Natural Course of Adolescent Major Depressive Disorder: I. Continuity Into Young Adulthood - 07/09/11
Abstract |
Objective |
To examine the course of adolescent major depressive disorder (MDD) by comparing rates of mood and non-mood disorders between age 19 and 24 years in participants with a history of adolescent MDD versus participants with adolescent adjustment disorder with depressed mood, nonaffective disorder, and no disorder.
Method |
Participants from a large community sample who had been interviewed twice during adolescence completed a third interview assessing Axis I psychopathology and antisocial and borderline personality disorders after their 24th birthday: 261 participants with MDD, 73 with adjustment disorder, 133 with nonaffective disorder, and 272 with no disorder through age 18.
Results |
MDD in young adulthood was significantly more common in the adolescent MDD group than the nonaffective and no disorder groups (average annual rate of MDD = 9.0%, 5.6%, and 3.7%, respectively). Adolescents with MDD also had a high rate of nonaffective disorders in young adulthood (annual nonaffective disorder rate = 6.6%) but did not differ from adolescents with nonaffective disorder (7.2%). Prevalence rates of dysthymia and bipolar disorder were low (1%). Adolescents with adjustment disorder exhibited similar rates of MDD and nonaffective disorders in young adulthood as adolescents with MDD.
Conclusions |
This study documents the significant continuity of MDD from adolescence to young adulthood. Public health implications of the findings are discussed. J. Am. Acad. Child Adolesc. Psychiatry, 1999, 38(1):56–63.
Le texte complet de cet article est disponible en PDF.Key Words : major depressive disorder, recurrence, continuity, comorbidity, adolescents, adjustment disorder
This research was supported in part by NIMH awards MH50501, MH50522, and MH52858. |
Vol 38 - N° 1
P. 56-63 - janvier 1999 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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