Lithium tetrafluoroborate catalyzed highly efficient inter- and intramolecular aza-Michael addition with aromatic amines

Doi : 10.1016/j.crci.2011.09.006

U.P. Lad ^a, M.A. Kulkarni ^a, U.V. Desai ^a , P.P. Wadgaonkar ^b

Sous presse. Épreuves corrigées par l'auteur. Disponible en ligne depuis le samedi 05 novembre 2011

Abstract

Lithium tetrafluoroborate has been demonstrated for the first time to be an efficient catalyst in intermolecular aza-Michael addition aromatic amines to electron deficient alkenes. Suitability of the same catalyst in intramolecular aza-Michael addition leading 2-aryl-2,3-dihydroquinolin-4(1H) ones has also been described.

Keywords : Michael addition, Anilines, Lithium tetrafluoroborate, 2-aryl-2,3-dihydroquinolin-(4H)-1- ones