Publicité

Médecine

Paramédical

Autres domaines


S'abonner

Prevalence of diabetes and depressive symptomatology and their effect on mortality risk in elderly Italians: The Italian Longitudinal Study on Aging

Doi : 10.1016/j.diabet.2014.05.001 

F. Limongi  , M. Noale, G. Crepaldi, S. Maggi

ILSA Working Group

Voir les affiliations

Bienvenue sur EM-consulte, la référence des professionnels de santé.
L'accès au texte intégral de ce chapitre nécessite l'achat du livre ou l'achat du chapitre.

pages 6
Iconographies 1
Vidéos 0
Autres 0

Abstract

Aim

This study assessed the prevalence of depressive symptomatology (DS) in older individuals with diabetes to determine whether diabetes and DS are independent predictors of mortality, and if their coexistence is associated with an increased mortality risk.

Methods

Analyses were based on data from the Italian Longitudinal Study on Aging (ILSA), a prospective community-based cohort study in which 5632 individuals aged 65–84years were enrolled. The role of diabetes and DS in all-cause mortality was evaluated using the Cox model, adjusted for possible confounders, for four groups: 1) those with neither diabetes nor DS (reference group); 2) those with DS but without diabetes; 3) those with diabetes but no DS; and 4) those with both diabetes and DS.

Results

Type 2 diabetes mellitus (T2DM) was present in 13.8% of the participants; they presented with higher baseline rates of DS compared with the non-diabetic controls. During the first follow-up period, participants with DS but not diabetes had a 42% higher risk of all-cause mortality compared with the reference control group (HR=1.42; 95% CI: 1.02–1.96), while participants with diabetes but not DS had an 83% higher risk of death than the reference group (HR=1.83; 95% CI: 1.19–2.80). The risk of death for those with both disorders was more than twice that for the reference group (HR=2.58; 95% CI: 1.55–4.29). Analyses of deaths from baseline to the second follow-up substantially confirmed these results.

Conclusion

The prevalence rate of DS is higher in elderly people with diabetes and their coexistence is associated with an increased mortality risk.

Le texte complet de cet article est disponible en PDF.

Keywords : Diabetes mellitus, Depressive symptomatology, Elderly, Prevalence, Mortality risk


Plan


© 2014  Elsevier Masson SAS. Tous droits réservés.
Ajouter à ma bibliothèque Retirer de ma bibliothèque Imprimer

Vol 40 - N° 5

P. 373-378 - novembre 2014 Retour au numéro
Article précédent Article précédent
  • Adiponectin is expressed in the pancreas of high-fat-diet-fed mice and protects pancreatic endothelial function during the development of type 2 diabetes
  • X.-X. Liu, K.-Y. Liu, P. Li, S. Han, X.-D. Peng, L. Shen
| Article suivant Article suivant
  • Ethnic differences in the relationship between birth weight and type 2 diabetes mellitus in postmenopausal women
  • K.K. Ryckman, E. Rillamas-Sun, C.N. Spracklen, R.B. Wallace, L. Garcia, F.A. Tylavsky, B.V. Howard, S. Liu, Y. Song, E.S. LeBlanc, M.V. White, N.I. Parikh, J.G. Robinson

Bienvenue sur EM-consulte,
la référence des professionnels de santé.

Plus de 500 000 articles médicaux,
paramédicaux et scientifiques vous attendent.

L'accès au texte intégral de cet article nécessite un abonnement ou un achat à l'unité.

Déjà abonné à cette revue ?

Publicité