Huge strides were made in rheumatology during the last few years of the second millennium. Rheumatology is a fast-changing, more costly and more effective specialty than in the past. Joint Bone Spine accompanies and often ushers in these changes, while seeking to meet the informational needs of clinicians and researchers interested in rheumatology. Fifteen years of basic research into the role of TNFα in inflammatory joint disease have culminated in the development of effective anti-TNFα agents, new insights into the role of enzymes involved in inflammation have provided the rationale for designing novel anti-inflammatory agents, knowledge of the factors responsible for bone loss has opened up new avenues in the treatment of osteoporosis, work on nonspecific low back pain with or without sciatica has provided a clearer picture of triggering and exacerbating factors.
Every scientific journal seeks to make the information it carries available as quickly as possible to all those who may be interested. Joint Bone Spine, and its partner Elsevier, achieved this goal a few weeks ago by creating a website. All the texts published in Joint Bone Spine, the international edition of the French journal Revue du Rhumatisme, are accessible to all subscribers at http://www.Jointbonespine.com. As a special launching offer, this site will be accessible free of charge throughout the year 2001 to everyone, all over the world. All the scientific texts published in Joint Bone Spine, including the tables and figures, will be accessible immediately to all those likely to benefit from the information it contains, and to those who want to quote the articles where relevant. Also, the articles published in Joint Bone Spine will be entered into one of the largest database directly accessible via a computer, Science Direct (which contains the online unabridged versions of 1200 journals published by Elsevier Science). Institutions (libraries, universities, hospitals, etc.) throughout the world can subscribe to Science Direct.
The profound changes that are redesigning the landscape of rheumatology, extending far beyond the area of therapeutics, are whisking rheumatologists into the twenty-first century. Joint Bone Spine is determined to serve as a medium to these changes, and thus to remain faithful to its past: the French version, Revue du Rhumatisme, is the oldest scientific publication in the world to focus on bone and joint diseases.