1Rheumatology Department, Rouen University Hospital Charles-Nicolle, Unit INSERM 519, IFR 23, 76000 Rouen cedex 76031, France
2 Bacteriology Department, Rouen University Hospital Charles-Nicolle, 76000 Rouen cedex 76031, France
*Correspondence and reprints: Service de Rhumatologie, Hôpital de Boisguillaume, Centre Hospitalier Universitaire de Rouen, 76031 Rouen cedex, France
In a man with osteoarthritis of the knee, Actinomyces naeslundii septic arthritis developed after intra-articular injection of hyaluronate. Actinomyces is an anaerobic Gram-positive rod. The outcome was favorable after treatment with two antibiotics and arthroscopy. The nature of the organism and its location to a joint are unusual features of this case, which illustrates the need to search for a septic complication before accepting a diagnosis of inflammation related to hyaluronate injection.
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