P02-173 Mild cognitive impairment and quality of life - 17/03/09
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Résumé |
Objective |
The aim of this study is to evaluate the influence of cognitive enhancers on quality of life to patients with MCI.
Material and methods |
The study comprises a number of 40 elderly patients diagnosed with mild cognitive impairment. These patients were divided in two groups:
• | group A that comprises 20 patients diagnosed with mild cognitive impairment that were treated with piracetamum (daily dose: 1600mg), |
• | group B that comprises 20 patients diagnosed with mild cognitive impairment that were treated with antioxidants Coenzima Q10 (daily dose: 15mg). |
MMSE score between 28-21points is considered mild cognitive impairment. The inclusion criteria were:
• | patients over 65 years, |
• | patients with mild cognitive impairment. |
• | The exclusion criteria were: |
• | patients with mild cognitive impairment due to major depressive disorder and schizophrenia, |
• | patients with moderate and severe cognitive impairment. |
• | The patients were evaluated with MMSE (Mini Mental State Evaluation) and GAF (Global Assessment of Functioning Scale) at the inclusion and after 6 months of treatment. |
Results |
The average of MMSE scores in group A was 25.9 and for group B 25.5. The patients treated with nootropics have had a better outcome, cognitive performance improving with 2,6 points for group A and with 1,8 points for group B. Improvement of cognitive performance improve the quality of life of this patients, the GAF scores improving from 45.4 points to 67.3 in group A and from 44.8 points to 55.3 in group B.
Conclusions |
The patients treated with nootopics have had a better outcome regarding cognitive functions and quality of life also. Improvement of cognitive performance improve the quality of life.
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Vol 24 - N° S1
P. S863 - 2009 Retour au numéro
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