Performance of glaucoma mass screening with only a visual field test using frequency-doubling technology perimetry - 02/09/11
for The Glaucoma Screening Project (GSP) Study Group⁎, b, c, d, e, f, ⁎, e1
InternetAdvance publication at ajo.com Sep 23, 2002.
Abstract |
PURPOSE: To report the performance of glaucoma mass screening with only a visual field test utilizing frequency- doubling technology (FDT) perimetry in general populations.
DESIGN: Hospital and population-based cross-sectional study.
METHODS: This study took place in a multicenter setting. One hundred three consecutive glaucomatous patients and 14,814 persons were randomly selected. We had created a glaucoma screening protocol (GSP) using FDT perimetry (FDT-GSP). Frequency-doubling technology-glaucoma screening protocol was tested on consecutive glaucoma patients diagnosed with Humphrey visual field analyzer (30-2 SITA standard), and then FDT-GSP was applied to general populations. Frequency-doubling technology-glaucoma screening protocol positive subjects were ophthalmologically diagnosed. Detection ability of FDT-GSP was determined in consecutive patients, and the positive predictive value (PPV) of FDT-GSP to detect definitive glaucoma was estimated in general populations.
RESULTS: Frequency-doubling technique-glaucoma screening protocol detected 83.3% and 100% of definitive glaucoma patients with an early (mean deviation [MD] > −6 dB) and more advanced stage (MD ≤ −6 dB), respectively. In the population-based screening, there were 660 (4.5%) subjects who had positive FDT-GSP, including 512 in whom no visual field abnormalities (VFA) had been pointed out previously. Of them, 370 subjects underwent ophthalmologic diagnosis. Then, 266 (71.9%, 266/370) subjects had a glaucomatous disk and 167 had definitive glaucomatous VFA. Fifty-five (14.9%) and 39 (10.5%) subjects were diagnosed as having other diseases and as normal, respectively. The PPV of FDT-GSP ranged from 32.6% (167/512)–45.1% (167/370).
CONCLUSIONS: Frequency-doubling technology-based screening with only a visual field test showed reasonable performance on mass screening for detection of definitive glaucoma in this study population, considering the glaucoma prevalence.
Le texte complet de cet article est disponible en PDF.Plan
Vol 134 - N° 4
P. 529-537 - octobre 2002 Retour au numéro
Article précédent
- A prospective randomized trial comparing intraoperative 5-fluorouracil vs mitomycin C in primary trabeculectomy
- Darrell WuDunn, Louis B Cantor, Angelita M Palanca-Capistrano, Joni Hoop, Nishat P Alvi, Charles Finley, Vipul Lakhani, Alan Burnstein, Stephenie L Knotts
- Optical coherence tomography measurement of nerve fiber layer thickness and the likelihood of a visual field defect
- Zinaria Y Williams, Joel S Schuman, Lisa Gamell, Ajit Nemi, Ellen Hertzmark, James G Fujimoto, Cynthia Mattox, Julie Simpson, Gadi Wollstein
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?