PEDIATRIC MASTOCYTOSIS - 04/09/11
Doi : 10.1016/S0889-8588(05)70299-9
Résumé |
Mastocytosis is a rare disorder characterized by accumulation of mast cells in tissues. Sixty-five percent of patients with mastocytosis are children. Whereas mastocytosis in adults is usually persistent or progressive, pediatric mastocytosis is often transient and limited. Recent studies suggest that childhood-onset and adult-onset mastocytosis also differ in their pathogenesis. This article reviews the various forms of pediatric mastocytosis with a special focus on new pathogenetic findings.
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| Address reprint requests to Dean D. Metcalfe, MD, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 10, Room 11C205, 10 Center Drive, MSC 1881, Bethesda, MD 20842–1881 |
© 2000
W. B. Saunders Company. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 14 - N° 3
P. 625-640 - juin 2000 Retour au numéro
Article précédent
- GASTROINTESTINAL ABNORMALITIES AND INVOLVEMENT IN SYSTEMIC MASTOCYTOSIS
- Robert T. Jensen
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- Lawrence B. Schwartz, Anne-Marie A. Irani
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