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Pratique neurologique - FMC
Volume 2, n° 4
pages 264-267 (décembre 2011)
Doi : 10.1016/j.praneu.2011.09.008
Cas remarquables

Encéphalite herpétique due au virus herpès simplex de type 2
Encephalitis due to herpes simplex virus type 2 (HSV-2)
 

S. Berroir , C. Henry
Service de neurologie, centre hospitalier Annemasse-Bonneville, 17, rue du Jura, BP 525, 74107 Annemasse cedex, France 

Correspondance. S. Berroir. Service de neurologie, centre hospitalier Annemasse-Bonneville, 17, rue du Jura, BP 525, 74107 Annemasse cedex, France.
Résumé

L’infection du système nerveux central par le virus herpès simplex de type 2 (HSV-2) est très rare chez l’adulte ; ce virus est responsable d’encéphalites chez des nouveau-nés contaminés par leur mère au moment de l’accouchement, et chez l’adulte de méningites parfois récurrentes, le plus souvent sans atteinte encéphalitique. Nous rapportons un cas d’encéphalite due au virus HSV-2 chez une adulte immunocompétente, remarquable par l’imagerie cérébrale, qui était normale malgré une aphasie, et par la composition du liquide céphalo-rachidien, qui présentait une forte pléiocytose et une hypoglycorachie.

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Summary

Adult central nervous system (CNS) infection due to herpes simplex virus type 2 (HSV-2) is rare. Newborns can be infected during delivery because of mother genital infection. Adult CNS infection causes most often a meningitis without brain involvement. We describe a case of encephalitis due to HSV-2 in an immunocompetent adult woman. This rare presentation was remarquable because of a normal brain imaging despite language impairment and cerebrospinal fluid high lymphocytosis with low glucose level.

The full text of this article is available in PDF format.

Mots clés : Herpès virus type 2, HSV-2, Encéphalite, Méningite, Méningo-encéphalite

Keywords : Herpes virus type 2, HSV-2, Encephalitis, Meningitis




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