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Journal of Neuroradiology
Sous presse. Epreuves corrigées par l'auteur. Disponible en ligne depuis le mardi 13 décembre 2011
Doi : 10.1016/j.neurad.2011.10.004
Primitive cerebral melanoma: A diagnostic and management challenge. About 2 cases
Mélanome cérébral primitif: un défi diagnostique et thérapeutique. À propos de 2 cas
 

L. Mondot a, ⁎ , F. Almairac b, F. Vandenbos c, D. Fontaine a, M. Frenay d, S. Chanalet a
a Department of radiology, Pasteur hospital, 30, avenue de la Voie-Romaine, CHU de Nice, 06000 Nice, France 
b Department of neurosurgery, Pasteur hospital, 30, avenue de la Voie-Romaine, CHU de Nice, 06000 Nice, France 
c Department of pathology, Pasteur hospital, 30, avenue de la Voie-Romaine, CHU de Nice, 06000 Nice, France 
d Department of oncology, Antoine-Lacassagne center, 30, avenue de la Voie-Romaine, CHU de Nice, 06000 Nice, France 

Corresponding author. Tel.: +33 04 92 03 77 18.
Summary

In this report of two cases of solitary cerebral meningeal melanoma, a rare tumor that presents both diagnostic and management challenges, the diagnosis of these lesions was based on a solitary leptomeningeal mass on MRI, a high mitotic rate on histology and the absence of extracerebral localizations. Although the radiological patterns can mimic those of other melanocytic tumors, MRI is a useful diagnostic tool for narrowing the differential diagnosis. Surgical removal remains the only effective treatment of these lesions, and can lead to prolonged survival in a few cases.


Keywords : Primary melanoma, Leptomeninges, Melanocytic tumor


OutlineMasquer le plan
Introduction
Case report  (+)
Discussion
Conclusion
Disclosure of interest


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