Access to the full text of this article requires a subscription.
  • If you are a subscriber, please sign in 'My Account' at the top right of the screen.

  • If you want to subscribe to this journal, see our rates


@@#116300@@

Journal of Neuroradiology
Sous presse. Epreuves corrigées par l'auteur. Disponible en ligne depuis le vendredi 23 décembre 2011
Doi : 10.1016/j.neurad.2011.11.005
Comparison of NASCET and WASID criteria for the measurement of intracranial stenosis using digital subtraction and computed tomography angiography of the middle cerebral artery
Comparaison des critères NASCET et WASID pour la mesure de la sténose intracrânienne par angiographie conventionnelle et angioscanner de l’artère cérébrale moyenne
 

Jun Huang a, Andrew J. Degnan b, Qi Liu a, Zhongzhao Teng b, Chen Shi Yue a, Jonathan H. Gillard b, Jian Ping Lu a, ⁎
a Department of Radiology, Changhai Hospital, the 2nd Military Medical University, Shanghai, China 
b University Department of Radiology, University of Cambridge, Cambridge, UK 

Corresponding author. 168 Changhai Rd, Shanghai 200433, China. Tel.: +86 021 81873637; fax: +86 021 81873637.
Summary
Background and purpose

Intracranial large-artery atherosclerosis is considered a frequent cause of stroke worldwide, particularly in Asian populations. The current evidence suggests that symptomatic patients with severe stenosis may benefit from intracranial stents. There are two methods for calculating the degree of intracranial stenosis, Warfarin–Aspirin Symptomatic Intracranial Disease (WASID) and North American Symptomatic Carotid Endarterectomy Trial (NASCET), but they have never been compared.

Methods

A total of 25 patients with suspected middle cerebral artery (MCA) stenosis based on their acute presentation were imaged by computed tomography angiography (CTA), then confirmed by digital subtraction angiography (DSA). Measurements were carried out on symptomatic MCA using both methods for determining the degree of stenosis.

Results

The degree of stenosis was significantly different using NASCET and WASID methods in DSA (48.2% vs. 54.6%; P <0.01), whereas CTA values did not differ significantly (54.2% vs. 52.0%; P =0.9). All measurements were highly correlated between methods (Spearman r =0.92 and 0.89, respectively; P <0.01).

Conclusion

The results of this study suggest that NASCET and WASID measures are, on average, generally similar, although substantial disagreement in a given patient may be seen.


Keywords : Intracranial stenosis, Atherosclerosis, Stroke imaging, Cerebral angiography


OutlineMasquer le plan
Introduction
Methods  (+)
Results
Discussion
Disclosure of interest


© 2011  Published by Elsevier Masson SAS.
EM-CONSULTE.COM is registrered at the CNIL, déclaration n° 1286925.
As per the Law relating to information storage and personal integrity, you have the right to oppose (art 26 of that law), access (art 34 of that law) and rectify (art 36 of that law) your personal data. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.
Personal information regarding our website's visitors, including their identity, is confidential.
The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties.
Close
Article Outline