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Journal of Neuroradiology
Sous presse. Epreuves corrigées par l'auteur. Disponible en ligne depuis le vendredi 25 mai 2012
Doi : 10.1016/j.neurad.2012.03.005
Vertebral body osteolysis following the use of bone morphogenetic protein in spinal surgery: A mimicker of infection
 

Gaurav Saigal a , Robert Quencer a , James D. Guest b , Mircea M. Cristescu a, ⁎ , Nathan Lebwohl a
a Jackson Memorial Hospital, University of Miami Miller School of Medicine, 1611 NW 12th Avenue, Miami, FL 33136, USA 
b Lois Pope LIFE Center, University of Miami Miller School of Medicine, 1095 NW 14th Terrace, Miami, FL 33136, USA 

Corresponding author. Tel.: +305 585 7500, 727 744 4832; fax: +305 325 8591.
Summary

This report describes the imaging findings in three patients who developed lumbar spine osteolysis after posterior spinal fusion using rhBMP-2. These cases demonstrate the variable course of osteolysis, as well as the importance of recognizing its radiological appearances to prevent confusion with infection following spinal fusion.


Keywords : Bone morphogenetic protein, BMP, RhBMP-2, Osteolysis, Bone resorption, Interbody fusion, Lumbar spine, Cervical spine


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Introduction
Clinical reports  (+)
Discussion
Disclosure of interest


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