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Comptes Rendus Chimie
Sous presse. Epreuves corrigées par l'auteur. Disponible en ligne depuis le samedi 14 juillet 2012
Doi : 10.1016/j.crci.2012.05.023
Received : 23 February 2012 ;  accepted : 30 May 2012
Synthesis, characterization and microbiocidal studies of novel ionic liquid tagged Schiff bases
 

Bharti Khungar a, ⁎ , Madharam Sudershan Rao a, Kasiviswanadharaju Pericherla a, Pankaj Nehra a, Navin Jain b, Jitendra Panwar b, Anil Kumar a, ⁎
a Department of Chemistry, Birla Institute of Technology and Science, 333031 Pilani, Rajasthan, India 
b Department of Biological Sciences, Birla Institute of Technology and Science, 333031 Pilani, Rajasthan, India 

Corresponding authors.
Abstract

The synthesis of novel imidazolium ionic liquid, tagged Schiff, has been described. The synthesis was achieved in three steps from 2,4-dihydroxybenzaldehyde by selective alkylation with 1,3-dibromopropane, followed by reaction with 1-methylimidazole and Schiff base formation with aromatic amines. The compounds were evaluated for antibacterial and antifungal activities. The ionic liquid tagged Schiff base 4a showed the inhibition of both Gram positive and Gram negative bacteria. It also showed broad spectrum antifungal activity against all four tested fungi; however, 4f showed highest antifungal activity against A. niger.


Keywords : Ionic liquid, Functionalized ionic liquid, Schiff base, Antibacterial, Antifungal


OutlineMasquer le plan
Introduction
Results and discussion
Conclusions
Experimental  (+)
In vitro antibacterial assay
In vitro antifungal assay


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