@@112058@@ : Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes

@@110897@@ @@107387b@@ dimanche 19 mai 2013

Diabetes & Metabolism
Volume 35, n° 2
pages 85-93 (avril 2009)

Doi : 10.1016/j.diabet.2008.10.003

Received : 3 July 2008 ; accepted : 7 October 2008

Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes
Les cellules souches mésenchymateuses comme nouvelle approche thérapeutique du diabète de type 1

Outline

Masquer le plan

Introduction

MSCs: definition, identification and immunomodulatory properties (+)

MSC therapeutic potential in type 1 diabetes: in vitro and in vivo evidence (+)

Controversial issues

Conflicts of interest


	Fig. 1

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Fig. 1 :

Immunomodulatory properties of mesenchymal stem cells (MSCs). TGFβ: transforming growth factor beta; PGE2: prostaglandin E2; IDO: indoleamine 2,3-deoxygenase; HGF: hepatocyte growth factor; IFNγ: interferon gamma; TNF⍺: tumour necrosis factor alpha; M-CSF: macrophage colony-stimulating factor; IL-6: interleukin-6; IL-12: interleukin-12.