Maximal stroke volume in children with repaired congenital heart disease - 14/08/18
Résumé |
Aims |
Maximal aerobic capacity (VO2 max) has already been reported in patients with congenital heart disease (CHD). We postulate CPET parameters does not reflect cardiac performance in these patients. We compared VO2 max and maximal systemic stroke volume (SV max) in a population of children with repaired CHD. Impedance cardiography is considered accurate for stroke volume (SV) measurement during exercise testing.
Materials and methods |
VO2 max and SV max (using impedance cardiography analysis device, Physioflox®) were measured during an upright ramp incremental cycle exercise in children with repaired congenital heart disease. Three groups were studied: G1 no residual disease n=23, G2 with residual left heart obstruction n=15, G3 with residual right heart obstruction and/or regurgitation n=40. The results were also compared with comparable healthy control population (G0 n=25).
Results |
No significant correlation between SV (mL/m2) and VO2 max and maximal oxygen pulse (% Th) was found in all the groups. Compared to controls (G0), stroke work was lower in patients with residual lesions (P<0.01) but was similar in patients with no lesions and controls. Peak SV was decreased significantly in G2 (49mL/m2) and G3 (46.95mL/m2) G0 with residual left or right lesions compared to G0 (G0 54.22mL/m2) P<0.001 while SV max in G1 was not impaired (57.8mL/m2).
Conclusion |
As expected, SV max was impaired in children residual lesion after CHD repair. VO2 max and maximal oxygen pulse does not seem to reflect cardiac performance. Concomitant noninvasive SV max measurement during CPET appears to be useful to evaluate these patients during their follow-up.
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Vol 10 - N° 3-4
P. 285 - septembre 2018 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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