Endocrine side-effects of new anticancer therapies: Overall monitoring and conclusions - 18/10/18
Consensus de la Société française d’endocrinologie sur la toxicité endocrinienne des nouveaux traitements anticancéreux : surveillance globale et conclusions
, Frédéric Albarel a, Françoise Archambeaud b, Jérome Bertherat c, Benjamin Bouillet d, e, Perrine Buffier d, Claire Briet f, Bertrand Cariou g, Philippe Caron h, Olivier Chabre i, Philippe Chanson j, Christine Cortet k, Christine Do Cao k, Delphine Drui g, Magali Haissaguerre l, Ségolène Hescot m, Frédéric Illouz n, Emmanuelle Kuhn j, Najiba Lahlou o, Emilie Merlen k, Véronique Raverot p, Sarra Smati g, Bruno Verges d, e, Françoise Borson-Chazot qAbstract |
The present final consensus statement of the French Society of Endocrinology lays out the assessments that are to be systematically performed before and during anticancer treatment by immunotherapy, tyrosine kinase inhibitors or mTOR inhibitors, even without onset of any endocrinopathy. It also discusses the CTCAE adverse event grading system in oncology and the difficulty of implementing it for endocrine side-effects of these anticancer treatments. Notably, this is why certain treatment steps applied in other side-effects (e.g., high-dose corticosteroids, contraindications to immunotherapy, etc.) need to be discussed before implementation for endocrine side-effects.
Le texte complet de cet article est disponible en PDF.Keywords : Immunotherapy, Tyrosine kinase inhibitors, MTOR inhibitors, Dysthyroidism, Hypophysitis, Diabetes, Dyslipidemia, Adrenal failure
Plan
Vol 79 - N° 5
P. 591-595 - octobre 2018 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
