Bacteriology of hidradenitis suppurativa/acne inversa: A review - 14/10/15
Abstract |
Given that follicular papules and pustules, as well as nodules and abscesses, are the clinical hallmarks of hidradenitis suppurativa (HS), an infectious, bacterial pathway has been suspected in the pathogenesis of this chronic, inflammatory condition. Elucidating the behavior and role of bacterial species in HS and their interaction with cutaneous innate immunity will provide more insight into the pathophysiology of this condition. This review of prospective investigations suggests a synergistic relationship between impaired innate immunity and microbial factors in the etiology of HS.
Le texte complet de cet article est disponible en PDF.Key words : acne inversa, actinomycetes, anaerobes, bacterial metagenomics, bacteriology, biofilm, hidradenitis suppurativa, milleri group streptococci, Staphylococcus lugdunensis
Plan
Drs Nikolakis, Join-Lambert, and Karagiannidis contributed equally to this manuscript. |
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Drs Zouboulis and Nassif contributed equally to this manuscript. |
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This publication was supported through funding provided by AbbVie Corporation. |
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Disclosure: Dr Karagiannidis has received a scholarship from Biogen-Idec. Dr Zouboulis has received honoraria from AbbVie, Almirall, Basilea, Bayer Health Care, Bioderma, Biogen-Idec, Dermira, Galderma, General Topics, Glenmark, Leo Pharma, Philips Lifestyle, Pierre Fabre, Stiefel/GSK, and Xenon for participation on advisory boards or as a consultant, investigator, or speaker; his department received grants from AbbVie, Astra Zeneca, Biogen Idec, Bristol Meyers Squibb, Immundiagnostik AG, Intendis, LVMH, Merz, Novartis, Pierre Fabre, and UCB for his participation as an investigator or on advisory boards. Dr Nassif has received travel compensation from MSD. Drs Nikolakis, Join-Lambert, and Guet-Revillet have no conflicts of interest to declare. |
Vol 73 - N° 5S1
P. S12-S18 - novembre 2015 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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