Efficacy of T-cell transcription factor–specific DNAzymes in murine skin inflammation models - 05/02/16

Doi : 10.1016/j.jaci.2015.09.022

Ulrich Purath, PhD ^a,^{^{∗
These authors contributed equally to this work.}}, Rouba Ibrahim, BSc ^b,^{^{∗
These authors contributed equally to this work.}}, Jana Zeitvogel, PhD ^c,^{^{∗
These authors contributed equally to this work.}}, Harald Renz, MD ^b, Frank Runkel, PhD ^d, Thomas Schmidts, PhD ^d, Dorota Dobler, PhD ^d, Thomas Werfel, MD ^c,^{^{∗
These authors contributed equally to this work.}}, Anke Müller, PhD ^a,^{^{∗
These authors contributed equally to this work.}}, Holger Garn, PhD ^b,^{^{∗
These authors contributed equally to this work.}}
^a Sterna Biologicals GmbH & Co. KG, Marburg, Germany
^b Medical Faculty, Institute of Laboratory Medicine and Pathobiochemistry – Molecular Diagnostics, Philipps University Marburg, Marburg, Germany
^c Clinic for Dermatology, Allergology and Venerology, Division of Immunodermatology and Allergy Research, Hannover Medical School, Hannover, Germany
^d Institute of Bioprocessengineering and Biopharmaceutical Technology, Technische Hochschule Mittelhessen, Giessen, Germany

The research reported in this article was supported by the German Federal Ministry of Education and Research, Bonn, Germany (grant no. 031A188); the German Federal Ministry of Economic Affairs and Energy, Bonn, Germany (grant no. KF2614701FR0); the HA Hessen Agentur, Wiesbaden, Germany; and Sterna Biologicals GmbH & Co. KG, Marburg, Germany. The content is solely the responsibility of the authors.

Disclosure of potential conflict of interest: U. Purath and A. Müller have received grants from the German Federal Ministry of Education and Research (grant no. 031A188), the German Federal Ministry of Economic Affairs and Energy (grant no. KF2614701FR0), and Hessen Agentur LOEWE-3 (grant nos. 137/07-01 and 205/09-35). R. Ibrahim has received travel support from Sterna Biologicals. J. Zeitvogel and T. Werfel have received grants from the German Federal Ministry of Economic Affairs and Energy (grant no. KF2117403FRO) and Sterna Biologicals. F. Runkel has received grants from Hessen Agentur LOEWE-3 (grant nos. 137/07-01 and 205/09-35) and Sterna Biologicals and has consultant arrangements with Engelhard Arzneimittel. T. Schmidts and D. Dobler have received grants from Hessen Agentur LOEWE-3 (grant nos. 137/07-01 and 205/09-35). H. Renz and H. Garn hold shares of and have received a consulting fee or honorarium from Sterna Biologicals.

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