P-096: Measure of change in carotid-radial pulse wave velocity after reactive hyperaemia - 12/02/16
Mesure des changements de la VOP carotido-radiale aprés hyperhemie réactive
Résumé |
Background |
The recognized reference method for endothelial function assessment is brachial artery diameter echo-tracking during flow mediated dilation (FMD) induced by reactive hyperaemia (RH). From the Mons-Korteweg equation, FMD should also reduce upper limb pulse wave velocity (PWV). The aim of our study was to compare echo-tracking FMD with PWV changes after RH.
Methods |
Brachial diameter was assessed by echo-tracking (MyLAb 70, Easote, Italy) before and after 7min of ischemia induced by inflating a cuff on the right wirst 50mmHg above subject's systolic blood pressure.
Carotid-left radial and carotid-right radial PWVs were also simultaneously measured with Complior Analyse (Alam Medical, France) at baseline (in triplicate), 30s, 1, 3 and 5min end of ischemia.
Measurements were performed in 15 healthy subjects (10M/5F, 31 ± 11 yrs).
Results |
Maximum PWV changes happened 1min after cuff deflation in the ischemic arm (δPWV=2,1±1,4m/s, p<0,001) while changes in the control arm were non-significant.
The maximal change in arterial diameter post-RH was 5,1±4,7%. There was no correlation between diameter change and δ PWV (R=0,03, p=0,91).
Conclusions |
While the use carotid-radial PWV seems promising to track changes post RH, further studies are needed to better understand this phenomena which is not related to diameter change.
Abstract P-096 – Figure
Abstract P-096 – FigureLe texte complet de cet article est disponible en PDF.
Vol 64 - N° S1
P. S56 - décembre 2015 Retour au numéro
Article précédent
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