0202: Predictive factors of left ventricular recovery in acute heart failure revealing reduced left ventricular ejection fraction - 12/02/16
Résumé |
Aims |
Evaluate the factors presents at diagnosis associated to left ventricular recovery in acute heart failure (AHF) revealing reduced left ventricular ejection fraction (LVEF).
Background |
A lot of paperwork have studied the left ventricular evolution in chronic heart failure but not in AHF and indistinctly of LVEF. We don’t know the predictive factors of left ventricular recovery in a specific population of acute heart failure revealing reduced LVEF.
Methods |
We conducted a prospective and observational longitudinal study with retrospective data collection based on a cohort of patients with acute heart failure revealing reduced LVEF (≤45%), in the emergency department and cardiac intensive care unit (ED and CCIU) of the University Hospital of Lille, between November 1st, 2011 and May 31st, 2013. The primary endpoint was the improvement of LVEF or left ventricular reverse remodeling.
Results |
Among the 111 patients included, 57% of patients benefited from an improvement of LVEF and 62% from a reverse remodeling in the 51% of patients with a dilated left ventricle. The improvement of LVEF was associated in univariate analysis to non ischaemic etiology (p=0.002) and greater utilization of betablockers (p=0.076) and angiotensin-converting enzyme (p=0.0337) and in multivariate analysis, independtly to younger patients (p=0.0325) and presentation by cardiogenic shock (p=0.0484). The same predictive factors were found for reverse remodeling.
Conclusion |
The knowledge of the prevalence and the early predictive factors of the left ventricular recovery can be useful to guide the follow-up and non-pharmacological management of heart failure with reduced LVEF.
Le texte complet de cet article est disponible en PDF.Vol 8 - N° 1
P. 26 - janvier 2016 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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