Coronary artery disease is a public health problem, whose prognosis and management depend on the development of lesions, hence the need to determine the profile of patients most at risk of developing major lesions, as well as items that can influence their prognosis.

The aim of our study is to identify the epidemiological profile of patients treated for acute coronary syndrome or explored for effort angina and have a documented three-vessel coronary disease. The second objective is to identify mortality factors.

This is a descriptive study that examined patients records hospitalized for coronary artery disease during the period from Jan 2007 to Dec 2012 and who have a three vessel coronary disease. The mean of follow up is 4 years.

During the period, 365 patients were hospitalized. This is 23% women and 77% of men (3.5 /1); the average age was 64 years for men VS 69 years for women (p<0.001). The reason for hospitalization was 44% of STEMI, 33% NSTEMI, 23% of effort angina. Diabetic patients accounted for 49%, 66% women vs 47% of men (p=0.001). Hypertension is present in 60% of patients. 34% of patients were smokers. Left ventricular function was impaired in 12% of cases. 213 patients (58%) had CABG (66% had diabetes (p<0.0001). 65 patients had an Angioplasty (13% of diabetics (p=0.01)) and 87 medical treatment alone. 52 patients died; These 32 men and 20 women. After the multivariate study, it was found that treatment with angioplasty was a factor of persistent angina after revascularization (OR=12). Diabetes (OR=3.27), and female gender (2.17) are mortality factors, regardless of the therapeutic decision. After revascularization, excess mortality was found in the angioplasty alone group (OR=6) diabetics (3.3) and females (2.5).

The multiple risk factor is a factor favoring triple vessel lesions. Mortality is higher in patients treated with angioplasty and even more so that they are diabetic women.