Recurrence of moderately dysplastic nevi with positive histologic margins - 18/04/17
Abstract |
Background |
The Pigmented Lesion Subcommittee of the Melanoma Prevention Working Group recently published a consensus statement that incompletely excised moderately dysplastic nevi (MDN) without clinical residual pigmentation can be observed and not re-excised. However, data regarding recurrence of MDN with positive histologic margins are quite scant.
Objective |
We sought to extend the reported findings with a study to determine the recurrence rate of MDN with positive histologic margins.
Methods |
We performed a retrospective study on MDN with positive histologic margins that were not re-excised and for which at least 1 year of clinical follow-up was available.
Results |
We found a total of 147 such nevi from January 1, 2007, to December 31, 2013. Six MDN (5 compound and 1 junctional) or 4% recurred with an average recurrence time of 1.7 years. All of these MDN were evaluated by shave biopsies.
Limitations |
Subjectivity in grading of atypia is a limitation of this study.
Conclusion |
These data from a large study focusing exclusively on recurrence of MDN with positive histologic margins support the conclusion of the Pigmented Lesion Subcommittee that incompletely excised MDN do not require re-excision.
Le texte complet de cet article est disponible en PDF.Key words : excision, histologic margins, moderately dysplastic nevi, observation versus re-excision, positive margins, recurrence, treatment of moderately dysplastic nevi
Abbreviations used : DN, MDN, PLS
Plan
| Funding sources: None. |
|
| Conflicts of interest: None declared. |
Vol 76 - N° 3
P. 527-530 - mars 2017 Retour au numéro
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