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Depression and Violence in Adolescence and Young Adults: Findings From Three Longitudinal Cohorts - 26/07/17

Doi : 10.1016/j.jaac.2017.05.016 
Rongqin Yu, PhD a, Mikko Aaltonen, PhD b, Susan Branje, PhD c, Tiina Ristikari, PhD d, Wim Meeus, PhD e, Katariina Salmela-Aro, PhD f, Guy M. Goodwin, MD a, Seena Fazel, MD a,
a University of Oxford, Oxford, UK 
b University of Helsinki, Helsinki, Finland 
c Utrecht University, Utrecht, The Netherlands 
d National Institute for Health and Welfare (THL), Oulu, Finland 
e Utrecht University and Tilburg University, Tilburg, The Netherlands 
f University of Jyväskylä, Jyväskylän, Finland 

Correspondence to Seena Fazel, MD, University of Oxford, Warneford Hospital, Oxford, OX3 7JX, UKUniversity of OxfordWarneford HospitalOxfordOX3 7JXUK

Abstract

Objective

Despite recent research demonstrating associations between violence and depression in adults, links in adolescents are uncertain. This study aims to assess the longitudinal associations between young people’s depression and later violent outcomes.

Method

We used data from three cohorts with different measurements of depression exposures and subsequent violent outcomes. In a Dutch community cohort Research on Adolescent Development And Relationships (RADAR; N = 623) and a population-based British birth cohort Avon Longitudinal Study of Parents and Children (ALSPAC; N = 4,030), we examined the longitudinal links between adolescent depressive symptoms and violent behaviors from age 13 to 17 years. In a total Finnish birth cohort (FBC 1987; N = 57,526), we estimated risk of violent convictions in individuals clinically diagnosed with depression from age 15 to 27 years.

Results

During a mean follow-up period of 4 years, the adjusted odds ratio (aOR) of violent behaviors per unit of increase in depressive symptoms was 1.7 (95% CI = 1.2–2.5) in the Dutch RADAR community sample and 1.8 (95% CI = 1.4–2.3) in the British ALSPAC birth cohort. In the FBC 1987 cohort, the aOR of violent convictions was 2.1 (95% CI = 1.7–2.7) among individuals with a depression diagnosis compared with general population controls without depression. All risk estimates were adjusted for family socioeconomic status and previous violence.

Conclusion

Consistent findings across three longitudinal studies suggest that clinical guidelines should consider recommending risk assessment for violence in young people with depression. The benefits of targeting risk management in subgroups by gender need further investigation.

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Key words : depression, violence, adolescents and young adults, longitudinal, birth cohort


Plan


 The research for this article is supported by a Rubicon Research Fellowship from the Netherlands Organisation for Scientific Research (NWO) to R.Y. (n. 446-15-002) and a Wellcome Trust Senior Research Fellowship to S.F. (n. 202836/Z/16/Z). G.M.G. is a senior investigator supported by National Institute for Health Research (NIHR). The RADAR cohort study has been financially supported by main grants from the Netherlands Organisation for Scientific Research (GB-MAGW 480-03-005, GB-MAGW 480-08-006), and Stichting Achmea Slachtoffer en Samenleving (SASS), a grant from the Netherlands Organisation for Scientific Research to the Consortium Individual Development (CID; 024.001.003), and various other grants from the Netherlands Organisation for Scientific Research, the VU University Amsterdam, and Utrecht University. The ALSPAC study has received core support from the UK Medical Research Council and the Wellcome Trust (Grant: 092731) and the University of Bristol. The FBC 1987 cohort study has been supported by two major grants from the Academy of Finland (n. 129283; n. 288960).
 The funders of this research had no role in the study design, analysis and interpretation of data, writing the report, or in the decision to submit the paper for publication. The views expressed are those of the authors and not necessarily those of the funders.
 Disclosure: Prof. Goodwin has served as a NIHR Senior Investigator, has received a grant from Wellcome Trust, has held shares in P1vital, and has served as consultant, advisor, or CME speaker for Angelini, Compass pathways, MSD, Lundbeck (/Otsuka or /Takeda), Medscape, P1Vital, Pfizer, Servier, and Shire. Drs. Yu, Aaltonen, Branje, Ristikari, Meeus, Salmela-Aro, and Fazel report no biomedical financial interests or potential conflicts of interest.


© 2017  American Academy of Child and Adolescent Psychiatry. Publié par Elsevier Masson SAS. Tous droits réservés.
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Vol 56 - N° 8

P. 652 - août 2017 Retour au numéro
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