Managing metastatic bone pain: New perspectives, different solutions - 08/08/17
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Abstract |
Bone metastases are the most frequent cause of cancer-induced bone pain (CIBP). Although palliative radiotherapy and pharmacotherapy conducted according to World Health Organization (WHO) analgesic ladder are the treatment of choice for CIBP reduction, these methods are not always successful, especially with regard to alleviation of incidental pain. Antiresorptive drugs (bisphosphonates) are able to inhibit bone destruction (loss), proliferation of cancer cells and angiogenesis, but their prolonged use may lead to a spectrum of adverse effects. In this paper, types of bone metastases, their complications, as well as diagnostic and therapeutic implications are presented. Moreover, the paper discusses presently used CIBP treatment methods and research directions for future methods, with special focus on bone metastases.
Le texte complet de cet article est disponible en PDF.Keywords : Bone pain, Bone metastases, Pathological fractures, Spinal cord compression, Antiresorptive drugs
Plan
Vol 93
P. 1277-1284 - septembre 2017 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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