Platelet-rich plasma-enriched autologous fat graft in regenerative and aesthetic facial surgery: Technical note - 07/09/17
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Abstract |
The goal of adding platelet-rich plasma (PRP) to autologous fat graft is to increase the survival rate of the graft. After their activation, platelets release some important growth factors. As a result, PRP may increase the proliferation and differentiation of Adipose-derived stem cells (ASCs) into adipocytes, improve fat graft vascularisation, and may block the apoptosis of grafted adipocytes. The other benefit expected from the addition of PRP to fat graft is the improvement of cutaneous trophicity above the grafted areas. An exhaustive review of the literature retrieved 11 clinical studies on humans and 7 on animals. A statistically significant increase of the survival rate of fat grafts has been found in 9 comparative studies. Our synthesis allowed us to set up the following protocol: addition of 20% of PRP activated with calcium hydrochloride to fat grafts. It may enhance the results of autologous facial fat graft in regenerative and aesthetic facial surgery.
Le texte complet de cet article est disponible en PDF.Keywords : Platelet-rich plasma, Autologous growth factors, Lipofilling, Fat graft, Fat transfer
Plan
☆ | Article reported from the 53rd SFSCMFCO Congress (Marseille, October 4–7, 2017) and published under the responsibility of the Scientific Committee of the congress. |
Vol 118 - N° 4
P. 228-231 - septembre 2017 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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