Inefficiency of ulipristal acetate on uterus leiomyomas as an additional sign to suspect leiomyosarcoma - 28/09/17
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Abstract |
The unexpected diagnosis of a leiomyosarcoma from a surgical specimen of a presumed leiomyoma is rare, but with deleterious consequences, especially if morcellation techniques are used. There are currently no effective methods for such a preoperative diagnosis. Ulipristal acetate has demonstrated efficacy for the preoperative treatment of leiomyomas, but not for all patients. We report two cases of leiomyosarcomas in patients treated with ulipristal acetate for a presumed leiomyoma. We propose that ineffective ulipristal acetate treatment may indicate a population in which uterine leiomyosarcoma is more prevalent. Attention should be given to any features of clinical and imaging examinations which raise the suspicion of a leiomyosarcomas in this population. Such suspicion should guide appropriate measures to avoid seeding the tumor, postponing the diagnosis, upstaging the patient and delaying the treatment (SPUD).
Le texte complet de cet article est disponible en PDF.Keywords : Hysterectomy, Leiomyosarcoma, Ulipristal acetate, Uterine morcellation
Abbreviations : Hysterectomy, Leiomyomas, Leiomyosarcomas
Plan
Vol 46 - N° 7
P. 609-611 - septembre 2017 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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