The effects of systemic corticosteroids on ultraviolet-induced delayed erythema were observed in a double-blind controlled study. The backs of human volunteers were irradiated with ultraviolet B (UVB) sources, and subsequent response was observed while ingesting prednisone (80 mg by mouth for 3 days) or placebo. Prednisone given 24 hours before, immediately after, 24 hours or 48 hours after exposure did not decrease the redness, edema, or tenderness of the exposed sites.
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Publié par Elsevier Masson SAS.