Photosensitization caused by ibuprofen - 06/10/17
Résumé |
Several nonsteroid antiinflammatory drugs (e.g., benoxaprofen, carprofen, and piroxicam) are known to induce photosensitivity reactions, but this has not yet been documented for ibuprofen. We observed a photosensitivity reaction in a patient treated with an oral ibuprofen preparation. This patient had a lowered minimal erythema dose for UVA but not for UVB after oral administration of ibuprofen. Results of a photopatch test with the drug were negative. In vitro UVA irradiation of human erythrocytes in the presence of ibuprofen caused ultraviolet dose-dependent phototoxic hemolysis.
Le texte complet de cet article est disponible en PDF.| Presented in part at the Forty-sixth Annual Meeting of the American Academy of Allergy and Immunology, Baltimore, Md., March 23–28, 1990. |
Vol 26 - N° 1
P. 114-116 - janvier 1992 Retour au numéro
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