Antinuclear antibody—negative systemic lupus erythematosus : I. Anti-Ro(SSA) and anti-La(SSB) antibodies - 07/10/17
Doi : 10.1016/S0190-9622(81)70013-6
Thomas T. Provost, M.D. ⁎, a, b, Morris Reichlin, M.D. a, b
a Baltimore, MD, USA
b From Johns Hopkins School of Medicine and the State University of New York at Buffalo, NY, USA
*Reprint requests to: Dr. Thomas T. Provost. The Johns Hopkins Medical Institution, Department of Dermatology, 600 W. Wolfe St., Baltimore, MD 21205.
Résumé |
Anti-Ro(SSA) and anti-La(SSB) antibodies are found in approximately 25% of systemic lupus erythematosus patients. These antibodies are also detected in lupus patients who fail to demonstrate a significant antinuclear antibody (ANA) titer when mouse liver is employed as the substrate. Approximately 5% to 10% of systemic lupus patients are in this category. These ANA-negative, Ro(SSA)-positive lupus patients generally demonstrate a prominent widespread photosensitive dermatitis and are frequently initially seen and evaluated by a dermatologist.
Le texte complet de cet article est disponible en PDF.© 1981
Publié par Elsevier Masson SAS.
Vol 4 - N° 1
P. 84-89 - janvier 1981 Retour au numéro
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