Analysis of hair from alopecia congenita - 07/10/17
Abstract |
Two patients with alopecia congenita had short vellus hairs of the scalp but some apparently normal-sized hairs in other areas. Both fibrous and matrix proteins were detected in the scalp hairs by polyacrylamide gel electrophoresis (PAGE), and x-ray diffraction analysis revealed a normal a pattern. Amino acid analysis showed a decreased cystine content suggesting a quantitative or qualitative change in the matrix component. Scanning electron microscopic examination revealed pits and bulges in the cuticle cells which may be related to wearing a wig. The data suggest a defect in the development of the follicle rather than an abnormality in a component of the hair.
Le texte complet de cet article est disponible en PDF.| * | Supported by Grant No. AM-06838 from the National Institute of Arthritis, Metabolism, and Digestive Diseases. |
| ** | We gratefully acknowledge Eila Kairinen of the Gillette Research Institute, Rockville, MD, for doing the scanning electron microscopy for this paper. |
Vol 3 - N° 6
P. 623-626 - décembre 1980 Retour au numéro
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