Drug-induced pemphigus related to angiotensin-converting enzyme inhibitors - 12/10/17
Résumé |
We report a case of drug-induced pemphigus caused by an angiotensin-converting enzyme inhibitor, Captopril. The cutaneous reaction remitted after withdrawal of Captopril therapy. Unique to this case, however, was the substitution of another angiotensin-converting enzyme inhibitor, enalapril, without exacerbation of the pemphigus. To the best of our knowledge, this is the first reported patient with captopril-induced pemphigus in whom no new lesions developed after subsequent treatment with enalapril. A difference in chemical structure between these two drugs, particularly of a sulfur moiety, may help explain why the drug-induced disease did not recur.
Le texte complet de cet article est disponible en PDF.Vol 26 - N° 2P2
P. 364-366 - février 1992 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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