Angiomatosis with luminal cryoprotein deposition - 12/10/17

Doi : 10.1016/0190-9622(92)70296-R

Philip E. LeBoit, MD ^{^{a
From the Departments of Pathology and Dermatology, University of California, San Francisco},}^⁎, Alvin R. Solomon, MD ^{^{b
the Department of Dermatology and Pathology, Emory University, Atlanta}}, Daniel J. Santa Cruz, MD ^{^{c
the Department of Cutaneous Pathology, St. John's Mercy Medical Center, St Louis}}, Mark R. Wick, MD ^{^{d
the Department of Pathology, Barnes Hospital, Washington University, St, Louis.}}
¹ San Francisco, California, USA
² Atlanta, Georgia, USA
³ St. Louis, Missouri, USA

^*Reprint requests: Philip E. LeBoit, MD, Department of Pathology, School of Medicine, University of California, San Francisco, CA 94143-0506.

Résumé

Background: Angioendotheliomatosis has recently been separated into two types. Malignant angioendotheliomatosis is a lymphoma in which the neoplastic cells accumulate in vascular lumens. Reactive angioendotheliomatosis is a proliferation of capillaries that is less well characterized.

Objective: Our purpose was to describe the clinical and histopathologic features of three cases of reactive angiomatosis in patients with cryoproteinemia.

Methods: Clinical and histologic data were correlated. Immunoperoxidase staining and electron microscopy were used in the histologic evaluation.

Results: All three cases showed tufts of capillaries with luminal deposits of apoproteins. Immunohistochemical studies showed that the cellularity of the tufts was primarily caused by a proliferation of pericytes.

Conclusion: Cryoproteinemia can cause angiomatosis that simulates a vascular neoplasm.

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Vol 27 - N° 6P1

P. 969-973 - décembre 1992 Retour au numéro

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Angiomatosis with luminal cryoprotein deposition - 12/10/17

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