Comparative effect of isotretinoin and etretinate on acne and sebaceous gland secretion - 12/10/17
Résumé |
Isotretinoin (13-cis-retinoic acid) was compared with the aromatic retinoid, etretinate, in patients with severe nodulocystic acne. Evaluation of fifty-six such men receiving 1 mg/kg of one or the other of these two drugs was performed with regard to clinical improvement and change in sebum production. Lesion counting demonstrated a significant improvement in patients receiving isotretinoin, particularly in facial lesions. There was significantly less improvement with etretinate. Similarly, isotretinoin produced a marked suppression of sebum production. There was little effect of etretinate on sebum production. Side effects were limited primarily to the skin and mucous membranes.
Le texte complet de cet article est disponible en PDF.Vol 6 - N° 4P2
P. 760-765 - avril 1982 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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