Lichen planus affecting the female genitalia: A retrospective review of patients at Mayo Clinic - 23/11/17
Abstract |
Background |
Genital or vulval lichen planus (VLP) may have a disabling effect on a patient's quality of life. Evidence-based management guidelines are lacking for VLP.
Objective |
We sought to review clinical presentation and treatment of patients who received a diagnosis of VLP.
Methods |
The 100 consecutive patients who received a diagnosis of VLP at Mayo Clinic between January 1, 1997, and December 31, 2015, were reviewed retrospectively. Descriptive statistics were used for data analysis. Fisher's exact test and the Wilcoxon rank sum test were used for analysis of categorical and continuous variables, respectively. All statistical tests were 2 sided, with the α level set at .05 for statistical significance.
Results |
The time to diagnosis for 49% of patients was more than 1 year. Three patients (3%) had vulval dysplasia, including invasive squamous cell carcinoma. Sixty-eight patients (68%) had multisite lichen planus disease. Eleven patients (11%) had disease remission. Dermatology was the lead specialty for 9 of these cases of remission.
Limitations |
This was a retrospective, small-cohort study.
Conclusion |
A low frequency of disease remission was seen in patients with VLP. Patients with lichen planus benefit considerably from dermatology consultation. Further research is warranted to establish high-quality, evidence-based guidelines for multidisciplinary management of this challenging disease.
Le texte complet de cet article est disponible en PDF.Key words : genital, gynecology, lichen planus, mucosal, therapeutics, vulvar
Abbreviations used : LP, SCC, SNP, VLP
Plan
| Supported in part by a grant from The City of Dublin Skin and Cancer Hospital Charity (to Dr Fahy). |
|
| Conflicts of interest: None declared. |
Vol 77 - N° 6
P. 1053-1059 - décembre 2017 Retour au numéro
Article précédent
- Demographic and health care service utilization by 4417 patients with hidradenitis suppurativa
- Guy Shalom, Meir Babaev, Tamar Freud, Shmuel Tiosano, Nadav Pam, Amir Horev, Jacob Dreiher, Daniel A. Vardy, Doron Comaneshter, Arnon D. Cohen
- Racial and ethnic differences in health care utilization for childhood eczema: An analysis of the 2001-2013 Medical Expenditure Panel Surveys
- Alexander H. Fischer, Daniel B. Shin, David J. Margolis, Junko Takeshita
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?