A new evidence-based risk stratification system for cutaneous squamous cell carcinoma into low, intermediate, and high risk groups with implications for management - 13/12/17
, Adam C. Wright, MD b, Juan-Carlos Martinez, MD c, Christopher J. Arpey, MD a, Jerry D. Brewer, MD a, Randall K. Roenigk, MD a, Clark C. Otley, MD aAbstract |
Most primary cutaneous squamous cell carcinomas are cured with surgery. A subset, however, may develop local and nodal metastasis that may eventuate in disease-specific; death. This subset has been variably termed high risk. Herein, we review; an emerging body of data on the risks of these outcomes and propose an evidence-based; risk stratification for low-, intermediate-, and high-risk tumors that takes into; account both tumor and patient characteristics. Finally, we discuss a framework for; management of these tumors on the basis of data, when available, and our; recommendations when data are sparse.
Le texte complet de cet article est disponible en PDF.Key words : cutaneous squamous cell carcinoma, immunosuppression, management, radiotherapy, risk stratification, sentinel lymph node biopsy, staging
Abbreviations used : ART, BWH, CLL, cSCC, CT, DSD, HRcSCC, IRcSCC, LR, LRcSCC, MMS, NM, PNI, SLNB
Plan
| Funding sources: Dr Baum has a Career Development Award in Dermatologic Surgery from the Dermatology Foundation. |
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| Conflicts of interest: None declared. |
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| Reprints not available from the authors. |
Vol 78 - N° 1
P. 141-147 - janvier 2018 Retour au numéro
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