Fused micro-computed tomography (?CT) and histological images of bone specimens - 11/07/18
, K. Laperre b, M. Halut a, C. Galant c, M. Van Cauter d, B.C. Vande Berg a
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Abstract |
Objectives |
To describe a stepwise process to obtain fused images from micro-computed tomography (μCT) and histological images of bone specimens.
Material and methods |
Four surgically resected human femoral heads from four patients who had total hip replacement were imaged at a spatial resolution of 12-microns by using μCT. Histological sections of four focal bone lesions including bone cyst in osteoarthritis (n=2) and subchondral bone plate fracture in osteonecrosis (n=2) were prepared and digitized. μCT images were reformatted and adjusted to match the histological images using a landmark-based visual co-registration. Fused μCT and histological images were displayed in a cine-loop video mode with a gradual transition from one image to the other.
Results |
μCT images of the four focal bone lesions could be successfully fused with the corresponding histological images with a near perfect match of the bone trabeculae.
Conclusion |
We present a stepwise process to obtain fused images from histological and reformatted μCT images of human femoral heads.
Le texte complet de cet article est disponible en PDF.Keywords : Micro-computed tomography (μCT), Histology, Radio-anatomical correlation, Femoral head, Image fusion
Plan
Vol 99 - N° 7-8
P. 501-505 - juillet 2018 Retour au numéro
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