Red meat and processed meat intake and risk for cutaneous melanoma in white women and men: Two prospective cohort studies - 16/07/18
Abstract |
Background |
Red and processed meat consumption has been associated with increased risk for several cancers, but the association with cutaneous melanoma risk has been inconclusive.
Objective |
To investigate the association between red and processed meat intake and melanoma risk.
Methods |
Dietary information was assessed by using food frequency questionnaires in 2 prospective cohorts: 75,263 women from the Nurses’ Health Study (1984-2010) and 48,523 men from the Health Professionals Follow-up Study (1986-2010). Melanoma cases were confirmed by reviewing pathology records. Pooled multivariable hazard ratios and 95% confidence intervals were estimated by using Cox proportional hazards models.
Results |
A total of 679 female and 639 male melanoma cases were documented during follow-up. Red and processed meat intake was inversely associated with melanoma risk (P = .002 for trend); the pooled hazard ratios (95% confidence intervals) of the 2 cohorts were 1.00 (reference), 1.00 (0.87-1.14), 0.98 (0.86-1.13), 0.89 (0.77-1.02), and 0.81 (0.70-0.95) for increasing quintiles of intake.
Limitations |
Findings might have limited generalizability, considering that the cohorts were limited to white health professionals.
Conclusion |
Red and processed meat intake was inversely associated with melanoma risk in these 2 cohorts.
Le texte complet de cet article est disponible en PDF.Key words : cutaneous melanoma, processed meat, prospective cohort study, red meat, skin cancer
Abbreviations used : BMI, CI, FFQ, HPFS, HR, NHS, NMSC, UV
Plan
Funding sources: Supported by the National Institutes of Health (CA186107, CA167552, and CA198216) and Research Career Development Award of Dermatology Foundation. |
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Conflicts of interest: None disclosed. |
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Reprints not available from the authors. |
Vol 79 - N° 2
P. 252 - août 2018 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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