Cosmetic dermatologic surgery has evolved to be a minimally invasive field that addresses patient concerns with a multimodal approach while minimizing adverse events and downtime. Within the armamentarium of dermatologic surgery, injections of soft tissue augmentation materials and neuromodulators are key tools for recontouring the aging face. Treatment of the individual patient is preceded by a comprehensive consultation that elicits patient concerns and preferences. A treatment plan is collaboratively developed to correct relevant deficits and retreat as appropriate to maintain the correction. The goal of volumization with fillers is to recreate atrophic subcutis and dermis, thereby filling the deflated face and returning it to a more youthful contour. Neurotoxins can help minimize the emergence of static wrinkles and selectively recontour the face. Treatment techniques for both filler and neurotoxin injections are customized for particular patient needs and are based on the type of deficit and the anatomic location.