Incidental findings on brain MRI in a cohort of diabetic patients - 24/08/18

Doi : 10.1016/j.neurad.2018.07.005

D. Vázquez-Justes ^a , J. Sanahuja ^a,^⁎ , J. Diez ^b , E. Rubinat ^c,^d , R. Begué ^b , C. Salas ^b , C. Vicandi ^b , M.I. Gil ^b , F. Purroy ^a , D. Mauricio ^d,^e
^a Department of neurology, universitat de Lleida, hospital Universitari Arnau de Vilanova Lleida, Clinical Neurosciences Group IRB, Lleida, Spain
^b Institut de diagnòstic per la imatge, hospital Universitari Arnau de Vilanova, Lleida, Spain
^c Faculty of nursing and physiotherapy, university of Lleida, GRECS Research Group of Biomedical Research Institute of Lleida, university of Lleida IRB, Lleida, Spain
^d CIBER of Diabetes and Associated Metabolic Diseases (CIBERDEM), instituto de Salud Carlos III, Madrid, Spain
^e Department of endocrinology & nutrition, hospital de la Santa Creu i Sant Pau, Barcelona, Spain

^⁎Corresponding author.

Sous presse. Épreuves corrigées par l'auteur. Disponible en ligne depuis le Friday 24 August 2018
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Abstract

Objective

To study the frequency and management of incidental findings in nonenhanced brain MRI of a middle-aged population of type 2 diabetic patients.

Methods

We retrospectively analyzed the results of 289 brain MRI obtained from subjects between 40–75 years recruited from a previous study. Incidental findings were classified into three categories: (1) Vascular findings; (2) neoplastic findings; and (3) others. On the other side, we made a classification of referral findings. To compare our results, we reviewed the prevalence and evidence about management of both incidental and referral findings in other series.

Results

We found an overall prevalence of incidental findings of 10.4% (30/289). Incidental findings raised according to age. The most common incidental findings were: 7 vascular (2.4%), 6 calcifications (2.1%), 6 cystic (2.1%) and 5 neoplastic (1.7%) lesions. A percentage of 1.7% (5/289) were referral findings which required further clinical work-up.

Conclusion

Incidental findings are relatively common in patients with type 2 diabetes. The most frequent are vascular findings, accordance with previous studies. Referral findings are uncommon. Clinical evidence about how to best manage the majority of incidental findings is lacking.

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Abbreviations : SVD, ADC, AVM

Keywords : Brain MRI, Incidental findings, Referral findings