The goal of this study was to demonstrate that the use of a splint after performing an osteosynthesis of the distal radius with a volar locking plate is unnecessary. The main hypothesis was that postoperative flexion of the wrist was greater without a splint. Secondary hypotheses were that patients who were allowed immediate mobilization got better results in terms of pain, Quick DASH, PRWE, strength, extension, pronation and supination. Our series included 72 patients, aged 59 years in average of which 59 were female patients. All patients had been operated for a volar locking plate fixation of a distal radius fracture. The first 36 patients (group I) were immobilized by a splint at 30° of extension of the wrist for 2 weeks. The 36 following patients (group II) were not immobilized. At 3 months, all the average variables were better in the group without splint (group I – flexion 74.83%, extension 83.13%, pronation 92.07%, supination 88.11%, pain 1.72 10, Quick DASH 21.78 100, PRWE 22.97 100, strength 62.96%) (group II – flexion 85.50%, extension 83.4%, pronation 92.96%, supination 92.96%, pain 1.28 10, Quick DASH 19.57 100, PRWE 20.56 100, strength 66.34%). No complication was reported. All in all, our results demonstrate that wearing a splint after volar locking plate fixation of a distal radius fracture is unnecessary.