Variation of kalemia and electrocardiographic predictors of sudden cardiac death along hemodialysis sessions - 25/12/18
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Résumé |
Introduction |
Sudden cardiac death (SCD) is the leading cause of death in hemodialysis (HD) patients, accounting for 20 to 30% of mortality in this population. Several electrocardiographic (ECG) predictors of cardiac arrhythmia responsible of SCD were previously defined. However, these predictors were less studied in HD population with divergent results.
Purpose |
The aim of our study is to evaluate different potential ECG predictors of SCD in parallel to kalemia variations in our HD population.
Methods |
We conducted a transversal study including 60 chronically dialysed patients. A kalemia dosage and an ECG recording immediately before and after HD sessions were performed. Then we evaluated, before and after dialysis, the variation of kalemia and ECG parameters: T wave and R wave amplitudes, T/R ratio, corrected QT interval (QTc), QRS duration and U wave.
Results |
Fourty-one males and nineteen females were studied with a mean age of 60 years old. Patients were chronically dialysed for a mean duration of 66 months (12 to 456 months). Diabetic nephropathy was the leading cause of hemodialysis (20%). Along HD sessions, a significant decrease of kalemia from 5.09±0.66mmol/L to 3.18±0.59mmol/L was detected (P=0.0001). In parallel, these ECG parameters significantly changed: T wave decreased, R wave increased and, as a result, T/R ratio decreased (Table 1).
Conclusion |
According to our study, we noted that, along HD sessions, with the decrease of kalemia, a significant decrease of T/R ratio occurred which may lead to a potential risk of cardiac arrhythmia and SCD.
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Vol 11 - N° 1
P. 110-111 - janvier 2019 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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