Coronary computed tomography angiography and predictive factors of coronary events in patients with non-valvular atrial fibrillation - 25/12/18
Résumé |
Background |
Clinical scores of thromboembolism risk (CHA2DS2-VASc) and hemorrhagic risk (HAS-BLED) have been developed to characterize the patients with non-valvular atrial fibrillation. These scores have been defined in part with clinical risk factors of atherosclerosis. Before their ablation, a coronary computed tomography angiography enables to determine the Agatston calcium score (coronary artery calcium score) which is a atherosclerosis marker.
Purpose |
In this study, tried to find out a link between the Agatston calcium score and the CHA2DS2-VASc, as well as between the Agatston calcium score and the HAS-BLED.
Methods |
Three hundred and forty-four atrial fibrillation subjects were included in our observational and retrospective study between January 1st, 2013 and January 1st, 2017, in the same institute. All of these patients had undergone a coronary computed tomography angiography.
Results |
Three hundred and seventeen patients were included in this study: 233 men (73.5%) and 84 women (26.5%), with an average age of 60,4 years. Agatston calcium score was significantly higher in the subjects with CHA2DS2-VASc score≥2 (P<0.00001); for men (P<0.000000001 for a CHA2DS2-VASc≥2) and for women too (P=0.03 for CHA2DS2-VASc≥3) (Table 1).
This link is also found between the Agatston calcium score and the HAS-BLED score≥2 (P<0.00000000001).
Conclusion |
This study shows a strong link between the atherosclerosis marker determined by CT (coronary artery calcium score), the thrombo-embolism risk score (CHA2DS2-VASc) and the hemorrhagic risk score (HAS-BLED) determined by clinical elements in patients with non-valvular atrial fibrillation.
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Vol 11 - N° 1
P. 17 - janvier 2019 Retour au numéro
Article précédent
- Is it always useful to prepare the femoral access before a coronarography?
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- M. Boukantar, E. Teiger, A. Cardio-ARSIF Investigators
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